Substituted indoles

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S397000, C514S384000, C514S376000, C514S307000, C514S369000, C548S312100, C548S264400, C548S229000, C548S187000, C544S238000, C546S148000

Reexamination Certificate

active

10516557

ABSTRACT:
The present invention relates to substituted indoles of formula (I) useful as pharmaceutical compounds for treating respiratory disorders

REFERENCES:
patent: 5459150 (1995-10-01), Brooks et al.
patent: 5486525 (1996-01-01), Summers, Jr. et al.
patent: 5567711 (1996-10-01), Sheppard et al.
patent: 2005/0222201 (2005-10-01), Birkinshaw et al.
patent: 0 530 907 (1993-03-01), None
patent: 0 576 347 (1993-12-01), None
patent: 0924209 (1999-06-01), None
patent: 1 170 594 (2002-01-01), None
patent: 1505061 (2005-02-01), None
patent: 1356834 (1974-06-01), None
patent: WO 94/19321 (1994-09-01), None
patent: WO 94/16687 (1995-06-01), None
patent: WO98/13368 (1998-04-01), None
patent: WO99/09007 (1999-02-01), None
patent: WO00/78761 (2000-12-01), None
patent: WO01/47922 (2001-07-01), None
patent: WO01/92224 (2001-12-01), None
patent: WO03/064387 (2003-08-01), None
patent: WO03/101961 (2003-12-01), None
patent: WO03/101981 (2003-12-01), None
patent: WO2004/007451 (2004-01-01), None
patent: WO2004/106302 (2004-12-01), None
patent: WO2005/019171 (2005-03-01), None
patent: WO2005/054232 (2005-06-01), None
Luscher et al., “Deblocking of o-Nitrophenylsufenyl-Protected Peptides by Ammonium Thiocyanate and (2-Methyl-1-indolyl)acetic acid”, Helv. Chim. Acta 66(2):602-605 (1983).
Atkinson et al., “A New Synthesis of 3-Arylthioindoles”,Synthesis6:480-481 (1988).
Garcia et al., “A Novel Synthesis of 3-Cyanoindoles and a New Route to Indole-3-Carboxylic Acid Derivatives”,Tetrahedron Letters26(15):1827-1830 (1985).
Hamel et al., “Regioselective Synthesis of Mixed Indole 2,3-Bis(sulfides). A Study of the Mechanism of the Second Sulfenylation of Indole”,J. Org. Chem.61:1573-1577 (1996).
Hary et al., “Efficient synthesis of 3-(4,5-dihydro-1H-imidazole-2-yl)-1H-indoles”,Tetrahedron Letters42:5187-5189 (2001).
Lüscher et al., “Deblocking of o-Nitrophenylsulfenyl-Protected Peptides by Ammonium Thiocyanate and (2-Methyl-1-indolyl) acetic acid”,Helv. Chim. Acta66(2):602-605 (1983).
Matsugi et al., “An efficient sylfenylation of aromatics using highly active quinone mono O,S-acetal bearing a pentafluorophenylthio group”,Tetrahedron Letters42:1077-1080 (2001).
Matsugi et al., “Facile and Efficient Sulfenylation Method Using Quinone Mono-O,S-Acetals under Mild Conditions”,J. Org. Chem.66:2434-2441 (2001).
STN International, CAPLUS accession No. 1977:535057, Document No. 87:135057, Sankyo Co., Ltd., “3-Indolyl thio ethers”, & JP,A2,52039671, 19770328, RN 64137-76-4, 54491-43-9, 56366-45-1.
STN International, CAPLUS accession No. 2001:338492, Document No. 134:353315, Wakunaga Pharmaceutical Co., Ltd., “Preparation of indole derivatives as chymase inhibitors and drugs containing the same as the active ingredient”, & WO,A1,2001032621, 20010510, RN 64137-76-4, 336186-33-5.
STN International, CHEMCATS accession No. 2000:1027702, Apr. 26, 2001, 8004-3013, “1H-Indole-1-acetic acid, 2-methyl-3-(phenylthio)-, ethyl esther”, CAS Registry No. 300860-50-8.
Database CA ′Online! Chemical Abstracts Service, Columbus, Ohio, US; Tanimoto, Norihiko et al: “Preparation of indole derivatives as PGD2 receptor antagonists” XP002301963 retrieved from STN Database accession No. 2003:931327.
Ovenden et al., “Echinosulfonic Acids A-C and Echinosulfone A: Novel Bromoindole Sulfonic Acids and a Sulfone from a Southern Australian Marine Sponge,Echinodictyum”, J. Nat. Prod.62:1246-1249 (1999).
STN International, CAPLUS accession No. 1980:6356, Document No. 92:6356, Gabrielyan, G.E. et al.: “Indole derivatives. LX. Synthesis of indole compounds with a furan ring”, & Armyanskii Khimicheskii Zhurnal (1979), 32(4), 309-14, RN 51842-57-0.
STN International, CAPLUS accession No. 2001:235566, Document No. 134:266203, Kato, Susumu et al.: “Preparation and application of benzopyranone derivatives”; & JP,A2,2001089471, 20010403, RN 332082-10-7.

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