Substituted imidazolinyl-imidazolines as antagonists of SH-2 bin

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514400, 514401, 514402, A01N 4350

Patent

active

057212660

ABSTRACT:
Methods of treating proliferative diseases or viral, inflammatory, allergic and cardiovascular diseases, and restenosis are disclosed. The present invention demonstrates the use of 2-amino-1-(2-imidazolin-2-yl)-2-imidazolines, and derivatives, and salts thereof, to antagonize the association of a protein tyrosine kinase with a substrate regulatory protein. The present invention also demonstrates the use of pharmaceutical compositions employing 2-amino-1-(2-imidazolin-2-yl)-2-imidazolines, and derivatives, and salts thereof, to antagonize the association of a protein tyrosine kinase with substrate regulatory protein. The present invention also relates to novel

REFERENCES:
patent: 3840554 (1974-10-01), Wittekind et al.
patent: 3905992 (1975-09-01), Wittekind et al.

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