Substituted imidazo[1,5-A]pyridines

Details Substituted imidazo[1,5-A]pyridines Substituted imidazo[1,5-A]pyridines

1982-06-01

1984-04-24

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546121, A61K 3141, C07D47104

Patent

active

044447752

ABSTRACT:
Disclosed are e.g. novel 5-(carboxyalkyl)imidazo[1,5-a]pyridines, their derivatives and methods of synthesis. Said compounds are useful as selective thromboxane synthetase inhibitors for the treatment of diseases such as cerebral ischaemia, shock, thrombosis and ischaemic heart disease.

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patent: 4273782 (1981-06-01), Cross et al.
patent: 4361567 (1982-11-01), Bristol et al.
patent: 4409226 (1983-10-01), Bristol et al.
Biochemical and Biophysical Research Communications, vol. 112 (3) 899-906 (1983).
O. Fuentes et al., J. Organic Chem. 40, 1210 (1975).
G. D. Durant et al., J. Medicinal Chem. 16, 1272 (1973).
W. W. Paudler et al., J. Heterocyclic Chem. 3, 33 (1966).
P. Blatcher et al., Tetrahedron Letters 21, 2195 (1980).

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