Substituted hydroxyethylamines

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Reexamination Certificate

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Details

C564S157000, C560S027000, C560S029000, C514S616000, C514S617000, C514S478000

Reexamination Certificate

active

10313849

ABSTRACT:
Disclosed are compounds of the formulaand the pharmaceutically acceptable salts thereof wherein the variables G, L, A, W, E, R2, R3, R4, R5, RN, and Rcare defined herein. These compounds interact with and inhibit the activity of the enzyme beta-secretase. These compounds are therefore useful in treating Alzheimer's disease and other similar diseases. Pharmaceutical compositions and methods of treatment of these diseases are also disclosed.

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