Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – N-c doai
Patent
1994-03-10
1995-11-07
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
N-c doai
514129, 514363, 514399, 514478, 514510, 514557, 514623, 514681, 514689, 514712, 514715, 548129, 5483001, 560 31, 558428, 562500, A61K 3127
Patent
active
054648661
ABSTRACT:
Substituted hydrindanes and their use in controlling angiogenesis-dependent diseases in warm blooded animals are disclosed.
REFERENCES:
patent: 3836572 (1974-09-01), Franz
patent: 4594432 (1986-06-01), Baggiolini et al.
patent: 4758382 (1988-07-01), Sterling et al.
patent: 5346701 (1994-09-01), Heiber et al.
BenEzra, "Neovasculogenic ability of prostaglandins, growth factors and synthetic chemoattractants," American J. Ophthalmology, 86:445-461, Oct., 1978.
Crum et al., "A new class of steroids which inhibits angiogenesis in the presence of heparin or a heparin fragment," Science, 230:375-378, 20 Dec. 1985.
Doctrow & Kulakowski, "Angiogenesis modulators--New drugs for controlling blood vessel growth?" Drug News & Perspectives 2:74-81, Mar., 1989.
Folkman et al., "Angiogenic factors," Science 235:442-447, 1987.
Furcht, "Critical factors controlling angiogenesis: cell products, cell matrix and growth factors," Laboratory Investigation, 55:505-509, 1986.
Ingber & Folkman, "Inhibition of Angiogenesis through modulation of collagen metabolism," Laboratory Investigation, 59:44-51, 1988.
Ingber et al., "Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumor growth," Nature, vol. 348:555-557, 6 Dec. 1990.
Javier Sardina, F., et al., J. Org. Chem. 51:1264, 1986.
Johnson, W. S., et al., J. Am. Chem. Soc. 106:1138, 1984.
Johnson, W. S., et al., J. Org. Chem. 50:2598, 1985.
Li et al., "Angiostatic steroids potentiated by sulphated cyclodextrin inhibit corneal neovascularization," Investigative Ophthalmology and Visual Science, 32:2898-2905, Oct., 1991.
Maione & Sharpe, "Development of angiogenesis inhibitors for clinical applications," Trends in Pharmaceutical Sciences, 11:457-461, Nov. 1990.
Maione et al., "Inhibition of angiogenesis by recombinant human platelet factor-4 and related peptides," Science, 247:77-79, 5 Jan. 1990.
McNatt et al., "Angiostatic activity and metabolism of cortisol in the chorioallantoic membrane (CAM) of the chick embryo," J. Steroid Biochem. Molec. Biol. vol. 42:687-693, 1992.
Oikawa et al., "A highly potent antiangiogenic activity of retinoids," Cancer Letters, 48:157-162, 1989.
Oikawa et al., "Powerful antiangiogenic activity of herbimycin A, " The Journal of Antibiotics, XLII: 1202-1204, Jul, 1989.
Oikawa et al., "Inhibition of angiogenesis by vitamin D.sub.3 analogues," European J. Pharmacology, 178:247-250, 1990.
Clark Abbot F.
Conrow Raymond E.
Alcon Laboratories Inc.
Burn Brian M.
Raymond Richard L.
Ryan Patrick M.
Yeager Sally
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