Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-10-17
2006-10-17
Zucker, Paul A. (Department: 1621)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S438000, C514S471000, C514S602000, C514S603000, C548S503000, C549S074000, C549S492000, C564S085000, C564S086000
Reexamination Certificate
active
07122571
ABSTRACT:
Compounds useful as inhibitors of cyclooxygenase-2 activity have the formulae I or Ia:wherein: Q1, Q2, n, m, X, Y and R are as defined herein.
REFERENCES:
patent: 3629241 (1971-12-01), Krause et al.
patent: 4656184 (1987-04-01), Coquelet et al.
patent: 4732904 (1988-03-01), Morgan et al.
patent: 5072042 (1991-12-01), Janssen et al.
patent: 5665883 (1997-09-01), Baker et al.
patent: 69 22269 (1970-03-01), None
patent: 2297089 (1996-07-01), None
patent: 84/00007 (1984-01-01), None
Saduikis et al, Chemija, Synthesis of Substituted Arylsulfonylarylideneimines, Arylsulfonylhydrazones, and Arylhydrazones, 1993, vol. date 1992, (3), pp. 120-130.English Translation.
Shyam et al, Journal of Medicinal Chemistry 1985, 28 pp. 149-152.
Lespagnol et al, Bulletin de la Societe Chimique de France 1963, pp. 46-50.
Synthesis of Substituted Arylsulfonylarylidenimines, Arylsulfonylhydrazones, and Arylhydrazones. Saduikis, G.; Kazlauskas, D. Inst. Khim. Vilnius, Vilnius, Lithuania. Chemija (1993), vol. Date 1992, (3), 120-30. ISSN: 0235-7216.
Exploratory Laboratory Catalog, Ambinter Company, Paris, France, Updated in electronic database, Jan. 21, 2002, Catalog entry for “benzenesulfonamide, 4[[(4-methoxyphenyl)methylene]hydrazino]-,” CA registration No. 381692-57-5.
Krishnamurthy Shyam et al., “Relationship between structure and antineoplastic activity of (arylsulfonyl) hydrazones of 4-pyridinecarboxaldehyde”, Journal of Medicinal Chemistry, vol. 28, 1985, pp. 149-152.
Jesse A. May et al., “Antineoplastic properties of arylsulfonylhydrazones of 3-formylpyridazine 2-oxide and 4-formylpyrimidine 3-oxide”, Journal of Medicinal Chemistry, vol. 21, No. 12, 1978, pp. 1333-1335.
Patent Abstracts of Japan, vol. 004, No. 081 (C-014), Jun. 11, 1980 abstracting JP 55 045657 A.
Reddy E. Premkumar
Reddy M.V. Ramana
Drinker Biddle & Reath LLP
Monaco Daniel A.
Temple University - Of The Commonwealth System of Higher Educati
Zucker Paul A.
LandOfFree
Substituted hydrazones as inhibitors of cyclooxygenase-2 does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted hydrazones as inhibitors of cyclooxygenase-2, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted hydrazones as inhibitors of cyclooxygenase-2 will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3689308