Substituted hydantoins

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S371000

Reexamination Certificate

active

07371869

ABSTRACT:
The present invention relates to compounds of the formulawhich are useful in treating diseases characterized by the hyperactivity of MEK. Accordingly the compounds are useful in the treatment of diseases, such as, cancer, cognative and CNS disorders and inflammatory/autoimmune diseases.

REFERENCES:
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patent: WO 99/05117 (1999-02-01), None
patent: WO 01/83478 (2001-11-01), None
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C. F. Zheng et al.,J. Biol. Chem. 1993, 268, 11435.
S. Cowley et al.,Cell1994, 77, 841.
R. Seger et al.,J. Biol. Chem. 1992, 267, 14373.

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