Substituted hexatriene derivatives and their use in treating acn

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514544, 514570, 560 64, 562405, 548250, 548237, 558411, 564336, 544410, A61K 3141, A61K 3119, C07D25704, C07C 6304

Patent

active

048046701

ABSTRACT:
Substituted hexatriene derivatives of the formula I ##STR1## where R.sup.1 has the meaning given in the description, and their preparation, are described. The compounds may be used to treat acne and psoriasis.

REFERENCES:
patent: 4532343 (1985-07-01), Dawson et al.
Richard Moon, The Retinoids, vol. 2, "Retinoids and Cancer", pp. 327-371, Academic Press, 1984.
Marcia I. Dawson, Journal Med. Chem. (1984), "Conformationally Restricted Retinoids", pp. 1516-1531.

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