Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-07-27
1989-05-16
Bond, Robert T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514278, 546 18, 544231, A61K 31415, A61K 31305, C07D45000, C07D47120
Patent
active
048310352
ABSTRACT:
Certain substituted hexahydroarylquinolizines and pharmaceutically acceptable salts thereof are peripherally selective .alpha..sub.2 -adrenoceptor antagonists. The compounds are adapted to be employed for the treatment of certain pathological disorders such as hypertension, diabetes, disorders involving platelet aggregation and the like without side effects attributable to effect on the central nervous system.
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Baldwin John J.
deSolms Susan J.
Huff Joel R.
Vacca Joseph P.
Wiggins Jonathan M.
Bond Robert T.
Merck & Co. , Inc.
Robertson Alice O.
Sudol Michael C.
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