Substituted hexahydroarylquinolizines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514278, 546 18, 544231, A61K 31415, A61K 31305, C07D45000, C07D47120

Patent

active

048310352

ABSTRACT:
Certain substituted hexahydroarylquinolizines and pharmaceutically acceptable salts thereof are peripherally selective .alpha..sub.2 -adrenoceptor antagonists. The compounds are adapted to be employed for the treatment of certain pathological disorders such as hypertension, diabetes, disorders involving platelet aggregation and the like without side effects attributable to effect on the central nervous system.

REFERENCES:
patent: 4076820 (1978-02-01), Archibald et al.
patent: 4183937 (1950-01-01), Ward
patent: 4235910 (1980-11-01), White et al.
patent: 4328232 (1982-05-01), Ward et al.
patent: 4710504 (1987-12-01), Baldwin et al.

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