Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1989-02-06
1990-04-10
Bond, Robert T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
A61K 31505, C07D49520
Patent
active
049162233
ABSTRACT:
Certain substituted hexahydroarylquinolizines and pharmaceutically acceptable salts thereof are peripherally selective .alpha..sub.2 -adrenoceptor antagonists. The compounds are adapted to be employed for the treatment of certain pathological disorders such as hypertension, diabetes, disorders involving platelet aggregation and the like without side effects attributable to effect on the central nervous system.
REFERENCES:
patent: 4831035 (1989-05-01), Baldwin et al.
Baldwin John J.
deSolms Susan J.
Huff Joel R.
Vacca Joseph P.
Wiggins Jonathan M.
Bond Robert T.
DiPrima Joseph F.
Merck & Co. , Inc.
Robertson Alice O.
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