Substituted heteroarylphenyloxazolidinones

Details Substituted heteroarylphenyloxazolidinones Substituted heteroarylphenyloxazolidinones

1995-06-06

1997-08-05

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544237, 544238, 544335, 544336, 544353, 544283, 544116, 544139, 544127, 544122, 544120, 540603, 540601, 540600, 540599, 540598, 540597, 546122, 546113, 548232, C07D40310, C07D40110, C07D40314, C07D41310

Patent

active

056544286

ABSTRACT:
The present invention discloses novel substituted aryl- and heteroarylphenyloxazolidinones which are useful as anti-bacterial agents. More specifically, the substituted aryl- and heteroarylphenyloxazolidinones of the invention are characterized by oxazolidinones having aryl or heteroaryl group at the p-position of the 3-phenyl ring and additional substitutions at the m-position(s) of the 3-phenyl ring. A compound representative of this new class of oxazolidinones is (.+-.)-5-(acetamidomethyl)-3-[4-(3-pyridyl)-3,5-difluorophenyl]-2-oxazolid inone.

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