Substituted heteroarylalkanoic acids

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S333000, C546S270100, C546S256000

Reexamination Certificate

active

07361671

ABSTRACT:
Disclosed are substituted heteroarylalkanoic acids acids of the following formula D-A-C(O)R′, where D, A, and R′ are defined herein. These compounds are useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds and methods of treatment employing the compounds, as well as methods for their synthesis.

REFERENCES:
patent: 5990314 (1999-11-01), Daines
patent: WO 9322285 (1993-11-01), None
patent: WO 0123383 (2001-04-01), None
Mylari BL et al. J. Med. Chem. (1992) 35, 457-465.

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