Substituted fused pyrimidinones

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514262, 544255, 544262, 544265, 544278, 544280, A61K 31505, A61K 3152, C07D48700, C07D47300

Patent

active

052023281

ABSTRACT:
Novel substituted fused pyrimidinones of formula (I), which are useful as angiotensin II antagonists, are disclosed. ##STR1##

REFERENCES:
patent: 4870186 (1989-09-01), Aldrich et al.
patent: 4880804 (1989-11-01), Carini et al.
Chin et al., European Journal of Pharmacology, 157(1988) 13-21.
Piper et al., J. Med. Chem. (1980) 23(10) 1136-1139.
P. C. Wong et al., European J. Pharma., 202, p. 323 (1991).
Ziegler et al., J. Org. Che. 43(5) (1978).

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