Substituted fused bicyclic amines as modulators of chemokine...

Details Substituted fused bicyclic amines as modulators of chemokine... Substituted fused bicyclic amines as modulators of chemokine...

2007-06-12

2007-06-12

McKane, Joseph K. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S412000, C548S252000, C548S515000

Reexamination Certificate

active

11060483

ABSTRACT:
The present application describes modulators of CCR3 of formula (Ia) and (Ib):or pharmaceutically acceptable salt forms thereof, wherein Z, R1, R2, R3, R4, R5, R5′, R6, a, b, c, d, and u are as defined herein. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis using said modulators are disclosed.

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