Substituted furans and derivatives thereof acting at muscarinic

Details Substituted furans and derivatives thereof acting at muscarinic Substituted furans and derivatives thereof acting at muscarinic

1990-05-21

1991-11-26

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514374, 514397, 514406, 514422, 514444, 548203, 548235, 548336, 548374, 548517, 549 60, A61K 31415, C07D40506

Patent

active

050682377

ABSTRACT:
Substituted furans and derivatives thereof are described, as well as methods for the preparation and pharmaceutical compositions of same, which are useful as centrally acting muscarinic agents and are useful as analgesic agents for the treatment of pain, as sleep aids and as agents for treating the symptoms of senile dementia, Alzheimer's disease, Huntington's chorea, tardive, dyskinesia, hyperkinesia, mania, or similar conditions of cerebral insufficiency characterized by decreased cerebral acetylcholine production or release.

REFERENCES:
patent: 4061722 (1977-12-01), Rodor
patent: 4174451 (1979-11-01), Granados et al.
Danheiser et al., J. Am. Chem. Soc. (111), pp. 4407-4413, (1989).

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