Drug – bio-affecting and body treating compositions – Lymphokine – Interleukin
Patent
1992-05-29
1995-04-04
Wu, Shean
Drug, bio-affecting and body treating compositions
Lymphokine
Interleukin
514454, 514456, 549403, A61K 4505, A61K 3135, C07D31104
Patent
active
H00014273
ABSTRACT:
The use of substituted flavonoid compounds which have the immunomodulatory activity of (1) boosting natural killer activity in vivo and (2) inducing interferon, and (3) belong to the family of flavonoids of the formula (I): ##STR1## in conjunction with interleukin-2 in cancer therapy is disclosed.
REFERENCES:
patent: 4352792 (1982-10-01), Ishitsuka et al.
patent: 4602034 (1986-07-01), Briet et al.
patent: 4713465 (1987-12-01), Kramer et al.
patent: 4841077 (1989-06-01), Ito et al.
patent: 4938956 (1990-07-01), Howard et al.
patent: 5096707 (1992-03-01), Wiltrout et al.
patent: 5116954 (1992-05-01), Briet et al.
patent: 5126129 (1992-06-01), Wiltrout et al.
Chemical Abstracts 89:108951n (1978).
Chemical Abstracts 97:138315r (1982).
Chemical Abstracts 104:122574b (1985).
Chemical Abstracts 107:146923c (1987).
Futami et al., Cancer Research (Dec. 15, 1990) vol. 50, pp. 7926-7931.
Robert H. Wiltrout et al., "Flavone-8-Acetic Acid Augments Systemic Natural Killer Cell Activity And Synergizes With IL-2 For Treatment Of Murine Renal Cancer" The Journal Of Immunology, vol. 140, pp. 3261-3265 No. 9, May 1, 1988.
Baguley et al "1301" is the abstract of a poster session presentation made May 27, 1988, between 3:00 and 6:00 P.M., at the A.A.C.R. meeting in . . . .
Berthelon Jean-Jacques
Briet Phillipe
Collonges Francois
Hornung Ronald L.
Wiltrout Robert H.
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