Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-07-18
2006-07-18
Solola, Taofiq (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S365000, C514S374000, C424S009600
Reexamination Certificate
active
07078406
ABSTRACT:
The present invention is directed to a compound of Formula I:wherein A, R1, and R2are defined herein. The present invention is also directed to compositions comprising compounds of Formula I, methods of using compounds of Formula I, and methods of making compounds of Formula I.
REFERENCES:
patent: 5260207 (1993-11-01), Pantoliano et al.
patent: 5355215 (1994-10-01), Schroeder et al.
patent: 5463071 (1995-10-01), Himmelsbach et al.
patent: 5463564 (1995-10-01), Agrafiotis et al.
patent: 5962685 (1999-10-01), Ueda et al.
patent: 6020141 (2000-02-01), Pantoliano et al.
patent: 6037130 (2000-03-01), Tyagi et al.
patent: 6197258 (2001-03-01), Thompson et al.
patent: 6291191 (2001-09-01), Pantoliano et al.
patent: 6602702 (2003-08-01), McDevitt et al.
patent: WO 95/13067 (1995-05-01), None
patent: WO 97/14679 (1997-04-01), None
patent: WO 97/29774 (1997-08-01), None
patent: WO 97/42500 (1997-11-01), None
patent: WO 99.04780 (1999-02-01), None
patent: WO 01/06239 (2001-01-01), None
patent: WO 2001006253 (2001-01-01), None
patent: WO 01/71317 (2001-09-01), None
Diwu et al., 1997, Photochemistry and Photobiology, 66(4), pp. 424-431.
McDevitt et al., “Detection system based on an . . . ”, CAS:134:128190 (2001).
Bagshaw, C.R. and Harris, D.A., “Measurement of Ligand Binding to Proteins,” in Spectrophotometry & Spectrofluorimetry, Bashford, C.L., and Harris, D.A., eds., IRL Press, Oxford, England, (1987) pp. 91-113.
Barcelo, F., et al., “A Scanning calorimetric study of natural DNA and antitomoral anythracycline antibiotic-DNA complexes.” Chem.-Biol. Interactions (1990) 74: 315-324, Elsevier Scientific Publishers Ireland, Ltd.
Bell, J. E., “Fluorescence: Solution Studies,” in Spectroscopy in Biochemistry, vol. I, Bell, J. E., ed., CRC Press, Inc. Boca Raton, FL., (1981) pp. 155-194.
Bergeron, R.J., and McManis, J.S., “Total Synthesis of (±)-15-Deoxyspergualin,” J. Org. Chem. (1992) 52:2497-2502, American Chemical Society.
Bernatowicz, M.S., et al., “1 H-pyrazole-1-carboxamidine Hydrochloride: An Attractive Reagent for Guanylation of Amines and Its Application to Peptide Synthesis”, J. Org. Chem. (1992) 57:2497-2502, American Chemical Society.
Bernatowicz, M.S., et al., “Urethane Protected Derivitives of 1-Guanykpyrazole for the Mild and Efficient Preparation of Guanidines,” Tetrahedron Lett. (1993) 34:3389-3392, Pergamon Press, Ltd.
Brand, L., and Gohlke, J.R., “Fluorescence probes for structure,” Annu. Rev. Biochem. (1972) 41:843-868, Annual Reviews, Inc.
Brandts, J.F., and Lin, L-N., Study of Strong to Ultralight Protein Interactions Using Differential Scanning Calorimetry, Biochemistry (1990) 29:6927-6940, American Chemical Society.
Callis, P. R., et al., “The Theory of Two-Photon-Induced Fluorescence Anistrophy,” in Topics in Fluorescence Spectroscopy, vol. 5, Lakowicz, J. R., ed., Plenum Press, New York, NY (1997) pp. 1-42.
Clegg, R. M., et al., “Fluorescence Resonance Energy Transfer Analysis of the Structure of the Four-Way DNA Junction,” Biochemistry (1992) 31: 4846-4856, American Chemical Society.
Clegg, R. M., et al., “Observing the helical geometry of double-stranded DNA in solution by flurescence resonance energy transfer,” Proc. Natl. Acad. Sci. USA (1993) 90:2994-2998, National Academy Press.
Davidson, A.R. et al., “Cooperatively folded proteins in random sequence libraries,” Nat. Struct. Biol. (1995) 2:856-864, Nature Publishing Company.
Denk, W., et al., “Two-photon Laser Scanning Fluorescence Microscopy,” Science (1990) 248: 73-76, American Association for the Advancement of Science.
Diwu, Z., et al., “Fluorescent Molecular Probes II. The Synthesis, Spectral Properties and Use of Fluorescent Solvatochromic Dapoxyl™ Dyes,” Photochem. Photobiol. (1997) 66: 424-431, Allen Press.
Diwu, A., et al., “The Spectral Properties and Biological Applications of Solvatochromic Dapoxl™ Dyes,” in Advances in Fluorescence Sensing Technology IV, Lakowicz, J. R., et al., eds., S P I E-International Society for Optical Engineering, Bellingham, Washington, (1999), pp. 256-264.
Diwu, Z., et al. “Fluorescent molecular probes VI. The spectral properties and potential biological applications of water-soluble Dapoxyl™ sulfonic acid,” Journal of Photochemistry and Photobuilogy A: Chemistry (Feb. 2000) 131:95-100, Elsevier Science S. A.
Eftink, M.R., “The Use of Fluorscence Methods to Monitor Unfolding Tranisitions in Proteins,” Biophys. J. (1994) 66:482-501, The Biophysical Society.
Epps, D.E., et al., “The Ligand Affinity of Proteins Measured by Isothermal Denaturation Kinetics,” Anal. Biochem. (May 2001) 292:40-50, Academic Press.
Fedyunyaeva, I. A., and Shershukov, B.M., “4-(5-Aryl-2-oxazolyl) benzenesulfonic acid derivitives containing a dimethylamino group,” Khim. Geterotsikl. Soedin. (1993) 2:234-237.
Fersht, A., “Nucleation mechanisms in protein folding,” Curr. Opin. Struct. Biol. (1993) 7:3-9, Current Biology, Ltd.
Lee, M., et al., “In Vitro Cytoxicity of GC Sequence Directed Alkylating Agents Related to Distamycin,” J. Med. Chem. (1993) 36:863-870, American Chemical Society.
Maier, G.V. et al., “Spectral-luminescent properties of sulfonyl-substituted oxazole,” Zh. Prikl. Spektrosk. (1991) 55: 576-581.
Martson, F.A.O., “The purification of eukaryotic polypeptide synthesized inEscherichia coli,” Biochem, J. (1986) 240:1-12, The Biochemical Society.
Miller, A.E., and Bischoff, J.J. “A Facile Conversion of Amino Acids to Guanidino Acids,” Synthesis (1986) 9:777-779, Georg Thiem Verlag Stuttgart.
Ozaki, H., and McLaughlin, L.W., “The estimation of distances between specific backbone-labeled sites in DNA using fluorescence resonance energy transfer,” Nucl, Acids Res. (1992) 20:5205-5214, Oxford University Press.
Rockwell, P. L., and Storey, B.T., “Kinetics of Onset of Mouse Sperm Acrosome Reaction Induced by Solubolized Zona Pellucida: Fluorimetric Determination of Loss of pH Gradient Between Acrosomal Lumen and Medium Monitored by Dapoxl (2-Aminoethyl) Sulfonamide and of Intracellular Ca2+Changes Monitored by Fluo-3,” Mol. Reprod. Dev. (Mar. 2000) 55:335-349, Wiley-Liss, Inc.
Schellman, J.A., Communications to the editor. The effect of Binding on the Melting Temperature of Biopolymers (1976) 15: 999-1000, John Wiley & Sons, Inc.
Schellman, J.A., “The relation between the free energy of interaction and binding,” Biophys. Chem. (1993) 45:273-279, Elsevier Science Publishers B.V.
Schellman, J.A., “Macromolecular Binding,” Biopolymers (1975) 14:999-1018, John Wiley & Sons, Inc.
Shimada, K., and Mitamura, K., “Derivatization of thiol-containing compounds,” J. Chromatogr. B. Biomed. Appl. (1994) 659:227-241, Elsevier.
Skepper, J.N., et al., “How are Ca2+signals regulated by microtubules?” J. Physiol. (Sep. 2000) 527:72P, The Physiological Society.
Thompson, R.B., et al., “Improved fluorophores for zinc biosensing using carbonic anhydrase,” in Systems and Technologies for Clinical Diagnostics and Drug Discovery II, vol. 3603, Cohn, G.E., et al, eds., S P I E-International Society for Optical Engineering, (1999) pp. 14-22, Bellingham, Washington.
Thompson, R.B., et al., “Zinc biosensing with multiphoton excitation using carbonic anhydrase and improved flurophores,” J. Biomed. Opt. (Jan. 2000) 5:17-22, S P I E-International Society for Optical Engineering.
Volkov, V.M., et al., “Lasting in solutions of some diaryl-substituted oxazoles,” Zh. Prikl. Spektrosk (1979) 31: 635-638.
Weber, P.C., et al., “Structure-Based Design of Synthetic Azobenzene Ligands for Streptavidin,” J. Am. Chem. Soc. (1994) 116:2717-2724, American Chemical Society.
Wiseman, T., et al., “Rapid Measurement of Binding C
Carver, Jr. Theodore E.
Rinker James M.
Johnson & Johnson Pharmaceutical Research & Developmen
Shiao Robert
Solola Taofiq
Wilson Sonsini Goodrich & Rosati
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