Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-12-26
2006-12-26
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S236800, C544S137000, C546S208000, C548S240000
Reexamination Certificate
active
07153880
ABSTRACT:
The present invention relates to substituted diphenyl heterocycle compounds and pharmaceutical compositions thereof that inhibit replication of HCV virus. The present invention also relates to the use of the compounds and/or compositions to inhibit HCV replication and/or proliferation and to treat or prevent HCV infections.
REFERENCES:
patent: 2852503 (1958-09-01), Edward et al.
patent: 3189447 (1965-06-01), Neugebauer et al.
patent: 3257203 (1966-06-01), Klupfel et al.
patent: 3335149 (1967-08-01), Preston
patent: 3910942 (1975-10-01), Narayanan et al.
patent: 3964896 (1976-06-01), Neidermyer et al.
patent: 4087409 (1978-05-01), Preston
patent: 4405793 (1983-09-01), Fuchs et al.
patent: 4743521 (1988-05-01), Hoffmann et al.
patent: 4752324 (1988-06-01), Thomas et al.
patent: 4777258 (1988-10-01), Sitzmann
patent: 5151441 (1992-09-01), Mueller et al.
patent: 5256666 (1993-10-01), Mueller et al.
patent: 5463071 (1995-10-01), Himmelsbach et al.
patent: 5814627 (1998-09-01), Schwab et al.
patent: 6355669 (2002-03-01), Yamauchi et al.
patent: 6759538 (2004-07-01), Singh et al.
patent: 2002/0035156 (2002-03-01), Roniker et al.
patent: 2002/0049213 (2002-04-01), Weidner-Wells et al.
patent: 2004/0142985 (2004-07-01), Singh et al.
patent: 392520 (1965-10-01), None
patent: 559 195 (1975-02-01), None
patent: 21 37 719 (1973-02-01), None
patent: 27 21 955 (1978-11-01), None
patent: 100 32 874 (2002-01-01), None
patent: 563 686 (1993-03-01), None
patent: 0 776 894 (1997-06-01), None
patent: 0 927 992 (1999-07-01), None
patent: 1 459 375 (1966-04-01), None
patent: 02-146048 (1990-06-01), None
patent: 03-122652 (1991-05-01), None
patent: 04124178 (1992-04-01), None
patent: WO 93/17671 (1993-09-01), None
patent: WO 94/17059 (1994-06-01), None
patent: WO 95/24397 (1995-09-01), None
patent: WO 98/17652 (1998-04-01), None
patent: WO 98/47509 (1998-10-01), None
patent: WO 99/04390 (1999-01-01), None
patent: WO 99/20309 (1999-04-01), None
patent: WO 00/45799 (2000-01-01), None
patent: WO 00/40242 (2000-07-01), None
patent: WO 00/78726 (2000-12-01), None
patent: WO 02/20436 (2002-03-01), None
patent: WO 02/055025 (2002-07-01), None
patent: WO 03/040112 (2003-05-01), None
patent: WO 04/018463 (2004-03-01), None
patent: WO 04/103366 (2004-12-01), None
Roth, et al., “Zur Kondensation von Chalkonoxyden mit Hydroxylamin,” Arch. Pharm. 294, 769-774 (1961).
Kazimierz Samula, “Oksymowanic Azachalkonow,” Roczniki Chemll, Ann. Soc. Chim. Polonorum 45, 2063 (1971).
Kazimierz Samula, “Cyclization of Azachalcones and β-Hydroxyketones Oximes,” Roczniki Chemll, Ann. Soc. Chim. Polonorum 48, 959-964 (1974).
Robert K. Howe et al., “Nitrile Oxide Cycloaddition Routes to 2-(Isoxazol)-benzoates and 2-(1,2,4-Oxadiazol-3-yl)benzoates,” Heterocycl. Chem. 19(4), 721-726 (1982).
Elena Belgodere et al., “Studies on Isomeric Pyridylisoxazoles,” Heterocycles, 20(3), 501-504 (1983).
Sandor Batori et al., “Photoinduced Ring Transformation of Pyrido-[1,2-b]pyridazinium-4-olate,” Tetrahedron, 50(16), 4699-4708 (1994).
Takaki Kanbara et al., “Preparation of Soluble and Fluorescent Poly(arylene)s by 1,3-Dipolar Polycycloaddition and Properties of the Polymers,” Polymer Bulleting, 36, 673-679 (1996).
Yi-Yin Ku et al., “Use of Iodoacetylene as a Dipolarphilc in the Synthesis of 5-Iodoisxazole Derivatives,” Organic Letters, 3(26), 4185-4187 (2001).
Maybridge, plc, Trevillett, Tintagel, Catalog N. RF01996, Cornwall PL34 OHW, England.
Maybridge, plc, Trevillett, Tintagel, Catalog N. RF01972, Cornwall PL34 OWH, England.
Gatta et al. Synthesis of [1,2,4] Triazoloquinazoline and [1,2,4] Triazolo- 1,4-benzodiazepine derivatives. Journal of Heterocyclic Chemistry. (1993), vol. 30, pp. 11-16.
Database Chemcats Online! 1999m XP-002310049, Databased accession No. RN 247059-16-1.
Maybridge Hts, Order No. BTB 09742; RN 247059-16-1 Maybridge PLC, Trevillett, Tintagel, Cornwall, PL340HW, UK, Jan. 8, 2004 XP002297442.
STN File CA, Abstract 135:46129 & V.M. Barot et al, Asian Journal of Chemistry (2001), 13(1), pp. 341-343.
STN File CA, Abstract 132:265141 & S.V. Damle et al, Indian Journal of Heterocyclic Chemistry (1999), 9(2), pp. 81-86.
STN File CA, Abstract 132:180505 & V.R. Naik et al, Asian Journal of Chemistry (2000), 12(1), pp. 305-307.
STN File CA, Abstract 129:216539 & S.M. Naik et al, Oriental Journal of Chemistry (1998), 14(1), pp. 167-168.
STN File CA, Abstract 126:74789 & M. Shah et al, Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1996), 35B(12), pp. 1282-1286.
STN File CA, Abstract 122:81186 & S.R. Modi et al, Oriental Journal of Chemistry (1994), 10(1), pp. 85-86.
STN File CA, Abstract 118:191597 & T. Bandiera et al, Journal of Heterocyclic Chemistry (1992), 29(6), pp. 1423-1428.
Goff Dane
Issakani Sarkiz D.
Lu Henry
Singh Rajinder
Sun Thomas
McDonnell Boehnen & Hulbert & Berghoff LLP
Rigel Pharmaceuticals Inc.
LandOfFree
Substituted diphenyl heterocycles useful for treating HCV... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted diphenyl heterocycles useful for treating HCV..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted diphenyl heterocycles useful for treating HCV... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3716740