Substituted dihydrodibenzo/b,f/azepines, method of their prepara

Details Substituted dihydrodibenzo/b,f/azepines, method of their prepara Substituted dihydrodibenzo/b,f/azepines, method of their prepara

1996-06-27

1998-05-19

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540589, C07D22318, A61K 3155

Patent

active

057536465

ABSTRACT:
New compounds of general formula I, including all possible stereoisomers, are described ##STR1## wherein: R is hydrogen, alkyl, aminoalkyl, halogenalkyl, aralkyl, cycloalkyl, cycloalkylalkyl, alkoxy, phenyl or substituted phenyl or pyridyl group.
A process for their preparation consists of reaction of compound II ##STR2## with an acylating agent.

REFERENCES:
patent: 5466683 (1995-11-01), Sterling et al.
Drug Evaluation, vol. 43, No. 6., pp. 873-888, S. M. Grant and Diana Faulds, "Oxcarbazepine--A Review of its Pharmacology and Therapeutic Potential in Epilepsy, Trigeminal Neuralgia and Affective Disorders", 1992.
A. Korolkovas, Essentials of Medicinal Chemistry, 1988, John Wilson & Sons, New York, pp. 101-106.
R.C. Larock, Comprehensive Organic Transformations, 1989, VCH Publishers, pp. 966-972.

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