Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1979-05-09
1980-09-09
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
548341, A61K 31415, C07D23360
Patent
active
042218039
ABSTRACT:
There are provided 2,4-dichloro-4'-phenyl-.alpha.-(N-imidazolyl-methyl)-dibenzyl ether, 2,4-dichloro-4'-phenylthio-.alpha.-(N-imidazolyl-methyl)-dibenzyl ether and pharmaceutically acceptable acid addition salts thereof. These compounds show activity against some fungi, yeasts and gram positive aerobic and anaerobic bacteria. The new compounds can be prepared by condensing 1-(2',4'-dichlorophenyl)-2-(N-imidazolyl)-ethanol with 4-chloromethyl-biphenyl, 4-bromomethyl-biphenyl, 1-phenylthio-4-chloromethyl-benzene or 1-phenylthio-4-bromomethyl-benzene in a solvent, most preferably dimethylsulphoxide.
REFERENCES:
patent: 3717655 (1973-02-01), Godefroi et al.
patent: 4036973 (1977-07-01), Walker et al.
Massarani Elena
Nardi Dante
Tajana Alberto
Veronese Mario
Jiles Henry R.
Recordati S.A.
Schwartz Richard A.
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