Substituted dibenzo[a,d]cycloheptene NMDA antagonists

Details Substituted dibenzo[a,d]cycloheptene NMDA antagonists Substituted dibenzo[a,d]cycloheptene NMDA antagonists

1991-02-20

1996-04-16

Venkat, Jyothsan

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

C07D48708

Patent

active

055084010

ABSTRACT:
This invention involves novel neuroprotectant agents of the formula: ##STR1## in which R.sup.1 and R.sup.3 are, independently, hydrogen, cyano, nitro, halo or perhaloalkyl, with the proviso that one of R.sup.1 and R.sup.3 is other than hydrogen; R.sub.2 is alkyl; or a pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 3509158 (1970-04-01), Dobson et al.
patent: 3597433 (1971-08-01), Dobson et al.
patent: 4940789 (1990-07-01), Childers, Jr. et al.
patent: 5011834 (1991-04-01), Weber et al.
Brooks et al., J. Chem. Soc., Perkin I, 2588-2591 (1973).
Takayama et al., Chemistry Lett., 865-866 (1978).

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