Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-11-22
2005-11-22
Shameem, Golam M M (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S162000, C544S165000, C544S358000, C546S184000, C546S246000, C548S566000, C548S567000, C514S428000
Reexamination Certificate
active
06967199
ABSTRACT:
The present invention relates to novel substituted diamine derivatives for the formulawherein R1, R2, R3, R4, X1, X2, X3, X4, A, Y and n are as described in the specification, pharmaceutical compositions containing them and intermediates used in their manufacture. More particularly, the compounds of the invention are motilin receptor antagonists useful for the treatment of associated conditions and disorders such as gastrointestinal reflux disorders, eating disorders leading to obesity and irritable bowel syndrome.
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Johnson Sigmond G.
Rivero Ralph A.
Ciambrone Coletti Ellen
McKown Jeremy K.
Ortho-McNeil Pharmaceutical , Inc.
Shameem Golam M M
Shen Evelyn D.
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