Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-12-20
1995-01-10
Bernhardt, Emily
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514252, 514253, 544370, 544372, 544373, 544391, A61K 31495, C07D295192, C07D295185
Patent
active
053807260
ABSTRACT:
Substituted dialkylthio ethers of formula I ##STR1## wherein R.sub.1 -R.sub.6, alk, X and Y are as defined in the description, and salts thereof, exhibit properties inhibiting the biosynthesis of interleukin-1 (IL-1) and analgesic properties and can therefore be used as active ingredients in medicaments. They are prepared in a manner known per se.
REFERENCES:
patent: 3926961 (1975-12-01), Ferrini et al.
patent: 4505913 (1985-03-01), Ferrini et al.
patent: 4804661 (1989-02-01), Ferrini et al.
patent: 5011928 (1991-04-01), Venero
patent: 5286728 (1994-02-01), Ferrini
patent: 5321027 (1994-06-01), Ferrini et al.
J. Med Chem 26 (1983) pp. 1065-1070; Metz, et al. "Cloxacepride and Related Compounds . . . ".
J. Med. Chem. 33 (1990) 2883-91; Lis et al, "Synthesis of (Aryloxy)propanolamines and Related Compounds . . . ".
Chem Abstr. 100, 174, 780c (1984) Agarwal et al.
Chem. Abstr. 112, 235261f (1990), Botros et al.
Chem. Abstr 87 52957h (1977), Liebenow et al.
Chem. Abstr. 56, 10165c (1962), Jacob et al.
Derwent Abstr. 87-357055/51 corresponding to EP.250,361 (1986).
Chem Abstr. 57, 15126h (1962), Jacob et al.
Chem Abstr. 58, 3444e (1963), Jacob et al.
Chem. Abstr. 58, 4583f (1963), Rhone-Poulec.
Chem Abstr. 58, 10211 (1963), Jacob et al.
Bernhardt Emily
Ciba-Geigy Corporation
Fishman Irving M.
Kaiser Karen G.
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