Substituted di-t-butylphenols

Details Substituted di-t-butylphenols Substituted di-t-butylphenols

1986-08-27

1987-12-29

Reamer, James H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

560 16, 560 43, 560 44, 560110, 548253, 562431, 562454, 514535, 514539, 514562, 514381, A61K 31195, C07C10134

Patent

active

047161787

ABSTRACT:
Novel compounds which are 2,6-di-t-butylphenols substituted on the 4 position by an anilino group, which anilino group is substituted by a group which includes carboxyl, tetrazolyl or N-methyltetrazolyl are useful as inhibitors of leukotriene synthesis and as antiallergic agents. Pharmaceutical compositions containing such compounds and pharmacological methods for use of such compounds are also disclosed.

REFERENCES:
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patent: 3766280 (1973-10-01), Carney et al.
patent: 3773936 (1973-11-01), Shen et al.
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patent: 4510139 (1985-04-01), Bailey
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patent: 4528392 (1985-07-01), Mussen et al.
patent: 4568684 (1986-02-01), Rentzece
Derwent for Japanese Application 54758.
Goldstein et al., Helv. Acta. 11, 239-2451, (1928).

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