Substituted derivatives of thiamorpholinone

Details Substituted derivatives of thiamorpholinone Substituted derivatives of thiamorpholinone

1983-04-13

1984-11-20

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

C07D27912, A61K 740, A61K 3154

Patent

active

044839839

ABSTRACT:
A substituted derivative of thiamorpholinone, for use in the cosmetic and pharmaceutical field, has the formula ##STR1## wherein n is 0 or 1; R.sub.1 and R.sub.2 each independently represent hydrogen or lower alkyl and R.sub.3 represents hydrogen, mono or polyhydroxyalkyl containing 2-16 carbon atoms, carbamylalkyl, carboxyalkyl or alkoxycarbonylalkyl. When R.sub.3 represents hydrogen, R.sub.4 represents --CO.sub.2 R.sub.5 wherein R.sub.5 is alkyl having 3-18 carbon atoms, optionally interrupted by one or more heteroatoms, or mono or polyhydroxyalkyl having 2-18 carbon atoms. When R.sub.3 represents mono or polyhydroxyalkyl, carbamylalkyl, carboxyalkyl or alkoxycarbonylalkyl, R.sub.4 represents hydrogen or lower alkyl.

REFERENCES:
Basic Principles of Organic Chemistry, John D. Roberts and Marjorie C. Caserio, 1965, p. 563.

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