Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-09-25
1990-07-03
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549292, 546207, 546268, 548517, 548465, 548545, 548950, 514210, 514422, 514423, 514336, 514414, 514824, A61K 31345, C07D40502
Patent
active
049391437
ABSTRACT:
Disclosed are novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula ##STR1## and the corresponding ring-opened hydroxy acids derived therefrom and pharmaceutically acceptable salts thereof.
Pharmaceutical compositions containing said compounds and method of inhibiting the biosynthesis of cholesterol therewith are also disclosed.
REFERENCES:
patent: 4282155 (1981-08-01), Smith et al.
patent: 4308378 (1981-12-01), Stokken
patent: 4503072 (1985-03-01), Hoffman et al.
patent: 4567289 (1986-01-01), Willard et al.
patent: 4611067 (1986-09-01), Volante et al.
patent: 4622338 (1986-11-01), Baran et al.
patent: 4668699 (1987-05-01), Hoffman et al.
patent: 4681893 (1987-07-01), Roth
patent: 4772626 (1988-09-01), Smith et al.
Bruno Joseph G.
Neuenschwander Kent W.
Regan John R.
Balogh Imre (Jim)
Nicholson James A.
Raymond Richard L.
Rorer Pharmaceutical Corporation
Russell Mark W.
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