Substituted cyclohexanols as central nervous system agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514210, 514212, 5142275, 5142278, 5142355, 5142358, 514256, 514316, 514317, 514318, 514326, 514340, 514343, 540596, 540597, 540598, 540601, 544 60, 544 63, 544121, 544122, 544123, 544124, 544129, 544193, 544209, 544212, 544214, 544216, 544268, 544275, 544280, 544295, 544296, 544357, 544360, 544364, 544369, 544379, 546208, 546209, 546216, 546275, 546281, 546344, 548950, 548962, A61K 31495, A61K 3144, A61K 31445, A61K 31505, C07D40114, C07D40914

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049579215

ABSTRACT:
Substituted cyclohexanols are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful as central nervous system agents and are particularly useful as dopaminergic, antipsychotic, and antihypertensive agents as well as for treating hyperprolactinaemia-related conditions and central nervous system disorders.

REFERENCES:
patent: 4329353 (1982-05-01), Stokbroekx et al.
patent: 4762843 (1988-08-01), Caprathe et al.
Tamminga et al., Arch Gen Psychiatry, vol. 43, pp. 398-402 (1986).

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