Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1978-02-14
1979-05-08
Rollins, Alton D.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260239BE, 546213, 546223, 546284, 546304, 546312, 546303, 546290, 2603265L, C07D20722, C07D21172, C07D22304, C07D22502
Patent
active
041532350
ABSTRACT:
Compounds possessing hypoglycemic, hypotensive, anti-inflammatory, anticoagulant and diuretic acitivity are represented by compounds of the following formula ##STR1## wherein Y is thienyl, cycloalkyl of from 5 to 7 carbon atoms, phenyl or substituted phenyl in which case the substituents on the substituted phenyl are selected from halogen, such as fluorine, chlorine, bromine or iodine, lower alkyl of from 1 to 4 carbon atoms and lower alkoxy of from 1 to 4 carbon atoms; Z is hydrogen or hydroxy; R is hydrogen, lower alkyl of from 1 to 4 carbon atoms, phenyl or benzyl; R.sup.1 is hydrogen, lower alkyl of from 1 to 4 carbon atoms or halogen, such as chlorine, fluorine, bromine or iodine; m is from 3 to 6; and n is from 3 to 11. Pharmaceutical compositions of these compounds and their use are also disclosed.
Blohm Thomas R.
Grisar Johann M.
Roberts Edward M.
Rauchfuss, Jr. George W.
Retter Eugene O.
Richardson-Merrell Inc.
Rollins Alton D.
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