Substituted cycloalkanes

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...

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548407, 549 39, 549333, 260239A, 260465E, 546 15, 546230, 546231, 546234, 560 16, 560251, 564155, 564162, 564163, 564166, 424304, 424309, 424244, 424311, 424324, 424267, 424275, 424278, C07D48700, A61K 3140

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active

043605311

ABSTRACT:
[2-Amino(substituted cycloaliphatic)]benzeneacetamide and benzamide compounds, e.g., trans-3,4-dichloro-N-methyl-N-[7-(1-pyrrolidinyl)-1,4-dioxaspiro[4.5]dec-8 -yl]benzeneacetamide, have useful analgesic activity and low abuse or physical dependence liability, or are useful as chemical intermediates for producing such analgesic compounds. Processes for their preparation are disclosed. Pharmaceutical compositions and methods of use are also disclosed.

REFERENCES:
patent: 3510492 (1970-05-01), Szmuszkovicz
patent: 4065573 (1977-12-01), Lednicer
patent: 4098904 (1978-07-01), Szmuszkovicz
patent: 4145435 (1979-03-01), Szmuskovicz
patent: 4156733 (1979-05-01), Szmuszkovicz
patent: 4212878 (1980-07-01), Lednicer et al.

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