Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-08-27
1995-08-15
Richter, Johann
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 69, A61K 3148, C07D45700
Patent
active
054419611
ABSTRACT:
The present invention provides (8.beta.)-N-substituted cyclo or bicycloalkyl-6-(substituted)-ergoline-8-carboxamides useful for occupying 5HT.sub.2 or 5HT.sub.1c receptors in mammals. The invention also provides methods for treating a variety of disorders and conditions related to or affecting these receptors as well as pharmaceutical formulations of the compounds of the invention.
REFERENCES:
patent: 2997470 (1961-08-01), Pioch
patent: 3183234 (1965-05-01), Garbrecht et al.
patent: 3228944 (1966-01-01), Bernardi et al.
patent: 3580916 (1971-05-01), Garbrecht
patent: 4180581 (1979-12-01), Stadler
patent: 4609731 (1985-09-01), Jurgec et al.
patent: 4734501 (1988-03-01), Marzoni
patent: 4902691 (1990-02-01), Cohen et al.
patent: 4931447 (1990-06-01), Foreman et al.
patent: 4970314 (1990-11-01), Borner et al.
patent: 5043341 (1991-08-01), Cohen et al.
Derwent Abstracts 91-038417/06, abstracting EP 411494 (1991).
Derwent Abstracts 91-038418/06, abstracting EP 411495 (1991).
Chem. Abs., 54, 4925g (1960).
Derwent Abstracts 4840, abstracting Bel 603751 (1959).
Chem. Abs., 54, 14287g (1960).
Chem. Abs., 65, 3923b (1966).
Chem. Abs., 65, 3924b (1966).
Chem. Abs., 65, 3924f (1966).
Chem. Abs., 63, 13341b (1965).
Chem. Abs., 62, 4069b (1965).
Chem. Abs., 58, 557a (1963).
Chem. Abs., 58, 1501g (1963).
Derwent Astracts, 6972, abstracting Bel 625369 (1961).
Derwent Abstracts, 10,703, abstracting Bel 634886 (1962).
Derwent Abstracts, 7520, abstracting Bel 624577 (1961).
Floss et al., J. of Pharmaceutical Sciences, 62(5), 699-715 (1973).
The Pharmacological Basis of Therapeutics, 6th Ed., MacMillan Publishing Co., Inc., pp. 939-947 (1980).
Cohen Marlene L.
Robertson David W.
Eli Lilly and Company
Hydorn Michael
Jones Joseph A.
Richter Johann
Taylor Douglas J.
LandOfFree
Substituted cyclo or bicycloalkylamides of (8.beta.)-6-(substitu does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted cyclo or bicycloalkylamides of (8.beta.)-6-(substitu, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted cyclo or bicycloalkylamides of (8.beta.)-6-(substitu will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2181956