Substituted cyclic ureas and derivatives thereof useful as retro

Details Substituted cyclic ureas and derivatives thereof useful as retro Substituted cyclic ureas and derivatives thereof useful as retro

1996-08-21

1998-06-09

Gupta, Yogendra N.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514387, 514388, 5483031, 5483037, 5483111, 5483127, 5483225, 5483315, 5483321, A61K 31415, C07D23302

Patent

active

057634696

ABSTRACT:
The present invention relates to substituted cyclic ureas and analogs thereof of formula (I): ##STR1## wherein, T is selected from: --N(R.sup.22)C(.dbd.Z)N(R.sup.23)--; --N(R.sup.22)C(.dbd.Z)C(.dbd.Z)N(R.sup.23)--; --N(R.sup.22)S(.dbd.Z')N(R.sup.23)--; --N(R.sup.22)S(.dbd.Z').sub.2 N(R.sup.23)--; or --N(R.sup.22)P(.dbd.O)(R.sup.24a)N(R.sup.23)--;

REFERENCES:
patent: 3759933 (1973-09-01), Robison et al.
patent: 4174958 (1979-11-01), Pilgram
patent: 4894463 (1990-01-01), Blum
patent: 5095118 (1992-03-01), Poetsch et al.
patent: 5205861 (1993-04-01), Matrick
patent: 5250699 (1993-10-01), Casutt et al.
patent: 5276049 (1994-01-01), Himmelsbach et al.
patent: 5371102 (1994-12-01), Doerge
patent: 5436351 (1995-07-01), Coffey et al.
Dhas, S.K.; Wadodkar, S. G., and Kasture, A. V., Indian Drugs 1987, 25(3), 132, "Synthesis of 5-Ethoxy-1,3-disubstituted Benzimidazolin-2-thiones as Antiinflammatory-Analgesic Agents".
Laviell, Solange; Bory, Sonia; Moreau, Bernard; Luche, M. Jacqueline; and Marquet, Andree, J. Am. Chem. Soc. 1978, 100(5), 1558-63, "A Total Synthesis of Biotin Based on the Stereoselective Alkylation of Sulfoxides".
P.Y.S. Lam, P.K. Jadhav, C.J. Eyermann, C.N. Hodge, Y. Ru, L.T. Bacheler, J.L. Meek, M.J. Otto, M.M Rayner, Y.N. Wong, C.H.Chang, P.C.Weber, D.A. Jackson, T.R. Sharpe, S. Erickson-Viitanen, Science 1994, 263, 380-84, "Rational Design of Potent, Bioavailable, Nonpeptide Cyclic Ureas as HIV Protease Inhibitors".

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