Substituted cyclic sulphamide derivatives

Details Substituted cyclic sulphamide derivatives Substituted cyclic sulphamide derivatives

1992-02-20

1993-03-16

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514321, 514322, 514323, 514324, 514362, 544 8, 546209, 546271, 546273, 546274, 546280, 548134, A61K 31445, C07D41702, C07D28516, C07D28510

Patent

active

051944405

ABSTRACT:
A class of substituted cyclic sulphamide derivatives are selective agonists of 5-HT.sub.1 -like receptors and are therefore useful in the treatment of clinical conditions, in particular migraine and associated disorders, for which a selective agonist of these receptors is indicated.

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Design of Prodrugs, ed. H. Bundgaard, Elsevier, 1985.
Indian J. Chem., 1982, 21B, 941.
Chem. Ber., 1978, 111, 1915.
Protective Groups in Organic Chemistry, ed. J. F. W. McOmie, Plenum Press, 1973.
Protective Groups in Organic Synthesis, John Wiley & Sons, 1981.
J. Neurosci., 1987, 7, 894.
Arch. Pharm., 1990, 342, 111.
J. Org. Chem., 1982, 47 536.

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