Substituted cyclic carbonyls and derivatives thereof useful as r

Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

540489, 540542, 540545, 540553, 540575, 564 13, C07D24304, A61K 3155

Patent

active

056102941

ABSTRACT:
This invention relates to substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors, to pharmaceutical compositions comprising such compounds, and to methods of using these compounds for treating viral infection. A representative compound of the invention is the compound of formula: ##STR1## wherein R.sup.22 and R.sup.23 are allyl.

REFERENCES:
patent: 4749681 (1988-06-01), Evers et al.
Kondo et al., J. Antibiot. (1966) 19(3): 137-138.
Kefurt et al., Collect. Czech. Chem. Comm. (1984) 49(11): 2665-2673.
Van Dam et al., Carbohydr. Res. (1989) 187(1): 25-34.
Hirama et al., J. Am. Chem. Soc. (1985) 107: 1797-1798.
Kano et al., Chem. Pharm. Bull. (1985) 33(1): 340-346.
Moriconi et al., J. Org. Chem. (1972) 37(2): 208-214.
Wuts et al., J. Org. Chem. (1991) 56: 365-372.
Chim. Ther. (1968) 3: 321-324.
Monats. Chem. (1961) 92: 79-87.
Tetrahedron Lett. (1989) 30: 1253-1256.
J. Org. Chem. (1979) 44: 1391-1397.
Liebigs Ann. Chem. (1985) 275-300.
Tetrahedron Lett. (1987) 28: 3103-3106.
Tetrahedron Lett. (1987) 28: 5129-5132.
J. Org. Chem. (1982) 47: 1371-1373.
Orszanska and Rulko, Polish J. Chem. (1982) 56:1287-1296.
Kempf et al., J. Org. Chem. (1992) 57:5692-5700.
Newlander et al., J. Med. Chem. (1993) 36:2321-2331.
Chenera et al., Bioorganic & Med. Chem. Lett. (1993) 3:2717-2722.
Kempf et al., J. Med. Chem. (1990) 33:2687-2689.
Wittenberger et al. Tetrahedron (1993) 49:1547-1556.
Chemical Abstracts, 1987-1991 Chemical Substance Index, pp. 28157CS, 28906CS, 32617CS, and 78099CS.
Lam et al., Science (1994) 263:380-384.
Ghosh et al. Tet. Letters (1991) 32: 5729-5732.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Substituted cyclic carbonyls and derivatives thereof useful as r does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted cyclic carbonyls and derivatives thereof useful as r, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted cyclic carbonyls and derivatives thereof useful as r will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-444653

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.