Substituted cyclic amine compound, production process thereof an

Details Substituted cyclic amine compound, production process thereof an Substituted cyclic amine compound, production process thereof an

1995-12-19

1998-03-17

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514318, 514330, 546225, C07D21132, A61K 31445

Patent

active

057288356

ABSTRACT:
A substituted cyclic amine compound represented by the following general formula (1) ##STR1## wherein each of R.sup.1 to R.sup.5 represents a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group or the like, A represents a carbonyl group or a sulfonyl group, B represents a methine moiety or a nitrogen atom, D represents a methine moiety, a nitrogen atom or .dbd.N(.fwdarw.O)-- and n is an integer of 2 to 3; and synthetic methods thereof. The inventive compound is useful in preventing and treating circulatory organ-related diseases such as hypertension, ischemic heart disease, cerebrovascular disease, peripheral circulatory disease and the like.

REFERENCES:
patent: 5130313 (1992-07-01), Comte et al.
patent: 5229400 (1993-07-01), Hirosawa et al.
patent: 5231105 (1993-07-01), Shoji et al.

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