Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-06-26
2007-06-26
Seaman, D. Margaret (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C549S285000, C549S288000
Reexamination Certificate
active
10989057
ABSTRACT:
The present invention is directed to substituted coumarins and quinolines and analogs thereof, represented by the general Formula I:wherein A, B, X, Y, and Z are defined herein. The present invention also relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention can be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
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Cai Sui Xiong
Drewe John
Jiang Songchun
Kemnitzer William E.
Storer Richard
Cytovia, Inc.
Seaman D. Margaret
Sterne Kessler Goldstein & Fox P.L.L.C.
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