Substituted coumarin compounds

Details Substituted coumarin compounds Substituted coumarin compounds

1977-08-19

1980-05-27

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Virus

26034345, 2603452, 26032636, 26032685, 544 62, 544151, 544376, 546196, 546269, 424283, 424263, 549 60, C07D31116, A61K 3137, C07D40504

Patent

active

042050820

ABSTRACT:
New benzopyrane derivatives of the general formula ##STR1## in which R is free, esterified or amidated carboxyl, Ph is 1,2-phenylene which contains the group R--CO--NR.sub.3 -- and is otherwise unsubstituted or is substituted, X is a group of the formula --CO--CR.sub.1 .dbd.CR.sub.2 --, in which R.sub.1 and R.sub.2 independently of one another are hydrogen, acyl or a substituted or unsubstituted hydrocarbon radical or a hetero-analogue thereof, or conjointly are 3-membered to 5-membered lower alkylene, and R.sub.2 can also be free or etherified hydroxyl or hydroxyl etherified by an organic carboxylic acid, and R.sub.3 is hydrogen or lower alkyl, are useful as anti-allergic agents.

REFERENCES:
patent: 3008969 (1961-11-01), Pretka et al.
patent: 3201406 (1965-08-01), Moffett et al.
patent: 3792063 (1974-02-01), Cairns et al.
patent: 3937719 (1976-02-01), Sellstedt et al.
patent: 3947462 (1976-03-01), Hrendsen et al.

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