Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-12-12
1999-09-07
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514255, 514256, 514307, 514311, 514357, 514365, 514381, 514394, 514400, 514406, 514419, 514427, 514461, 544242, 544335, 544180, 546146, 546175, 546329, 548204, 548252, 5483097, 5483381, 5483751, 548495, 548561, 549 77, 549491, C07D21324, C07D21512, A61K 3134, A61K 3138
Patent
active
059487798
ABSTRACT:
Substituted condensation products of N-benzyl-3-indenylacetamides with heterocyclic aldehydes are useful for inducing or promoting apotosis and for arresting uncontrolled neoplastic cell proliferation, and are specifically useful in the arresting and treatment of neoplasias, including precancerous and cancerous lesions.
REFERENCES:
patent: 3161654 (1964-12-01), Shen
patent: 3312730 (1967-04-01), Winter et al.
patent: 3325358 (1967-06-01), Winter et al.
patent: 3532752 (1970-10-01), Shen
patent: 3609184 (1971-09-01), Miyai et al.
patent: 3622623 (1971-11-01), Shen et al.
patent: 3631167 (1971-12-01), Shen et al.
patent: 3642785 (1972-02-01), Shen et al.
patent: 3647858 (1972-03-01), Hinkley et al.
patent: 3654349 (1972-04-01), Shen et al.
patent: 3692651 (1972-09-01), Sletzinger
patent: 3692825 (1972-09-01), Conn
patent: 3700730 (1972-10-01), Hinkley
patent: 3737455 (1973-06-01), Shen et al.
patent: 3759987 (1973-09-01), Conn et al.
patent: 3766259 (1973-10-01), Sletzinger
patent: 3772282 (1973-11-01), Ford, Jr.
patent: 3812109 (1974-05-01), Shen et al.
patent: 3812180 (1974-05-01), Shen et al.
patent: 3822310 (1974-07-01), Shen et al.
patent: 3851063 (1974-11-01), Shen et al.
patent: 3860636 (1975-01-01), Shen et al.
patent: 3868414 (1975-02-01), Shen et al.
patent: 3868415 (1975-02-01), Jones
patent: 3869507 (1975-03-01), Jones
patent: 3870753 (1975-03-01), Tull et al.
patent: 3888902 (1975-06-01), Shen et al.
patent: 3897487 (1975-07-01), Jones
patent: 3932498 (1976-01-01), Shen et al.
patent: 3944600 (1976-03-01), Tull et al.
patent: 3954852 (1976-05-01), Shen et al.
patent: 3956363 (1976-05-01), Shen et al.
patent: 3970693 (1976-07-01), Tull et al.
patent: 3998875 (1976-12-01), Tull et al.
patent: 4207340 (1980-06-01), Gardocki
patent: 4233457 (1980-11-01), Czaja et al.
patent: 4307114 (1981-12-01), Dvornik et al.
patent: 4402979 (1983-09-01), Shen et al.
patent: 4423074 (1983-12-01), Dvornik et al.
patent: 4423075 (1983-12-01), Dvornik et al.
patent: 4656190 (1987-04-01), Shen et al.
patent: 4748271 (1988-05-01), Meneghin
patent: 4943587 (1990-07-01), Cetenko et al.
patent: 5112868 (1992-05-01), Cetenko et al.
patent: 5401774 (1995-03-01), Pamukcu et al.
Waddell, W.R. et al., Am. J. Surgery, vol. 157, pp. 175-179 (1989).
Gonzaga, R.A.F. et al., The Lancet, Mar. 30, 1985, p. 751.
Waddell, W.R. et al., J. Surg. Oncology, vol. 24, pp. 83-87 (1983).
Federation Proceedings (1972) of the Federation of American Societies for Experimental Biolgoy abstract Nos. 2044 and 2045 (1972).
Gilman, S.C. et al., Nonsteroidal Anti-inflammatory Drugs in Cancer Therapy, (circa 1985).
Brogden, R.N. et al., Drugs, vol. 16, pp. 97-114 (1978).
Hucker, H.B. et al., Drug Metabolism & Disposition, vol. 1, No. 6, pp. 721-736 (1973).
Shen, T.Y. et al., Chemical and Biological Studies on Indomethacin, Sulindac and Their Analogs, pp. 107-178 (circa 1975).
Duggan, D.E. et al., Clin. Pharm. & Therapeutics, vol. 21, No. 3, pp. 326-335 (1976).
Duggan, D.E. et al., J. Pharm. & Exper. Therap., vol. 201, No. 1, pp. 8-13 (1977).
Glavin, G.B. et al., Toxicology and Applied Pharmacology, vol. 83, pp. 386-389 (1986).
Moorghen, M. et al. Journal of Pathology, vol. 156, pp. 341-347 (1988).
Moorghen, M. et al., Acta histochemica, Suppl.-band XXIX, S. 195-199 (1990).
Bjarnason et al., Gastroenterology, vol. 94, No. 4, pp. 1070-1074 (1988).
Brendel Klaus
Gross Paul
Pamukcu Rifat
Piazza Gary A.
Sperl Gerhard J.
Cell Pathways Inc.
Rao Deepak R.
Shah Mukund J.
Stevenson Robert W.
LandOfFree
Substituted condensation products of n-benzyl-3-indenyl acetamid does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted condensation products of n-benzyl-3-indenyl acetamid, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted condensation products of n-benzyl-3-indenyl acetamid will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1804657