Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-06-10
2008-06-10
Chang, Celia (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S235800, C544S121000, C544S129000, C544S130000, C544S359000, C544S380000, C544S387000
Reexamination Certificate
active
07384943
ABSTRACT:
The present invention relates to new piperidyl- or piperazinyl-substituted dihydro-2H-1-benzopyran derivatives having the formula (I)whereinX is N;Y is NR2CH2, CH2NR2, NR2CO, CONR2, NR2SO2or NR2CONR2wherein R2is H or C1-C6alkyl;R1is H, C1-C6alkyl or C3-C6cycloalkyl;R3is C1-C6alkyl, C3-C6cycoalkyl or (CH2)n-aryl,wherein aryl is a heteromatic ring containing one or two heteroatoms selected from N, O and S and which may be mono- or di-substituted with R4and/or R5;and n is 0-4;as (R)-enantiomers, (S)-enantiomers or racemates in the form of a free base or a pharmaceutically acceptable salt or solvate thereof, a process for their preparation, pharmaceutical compositions containing said therapeutically active compounds and to the use of said active compounds.
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Berg Stefan
Nylöf Martin
Ross Svante
Thorberg Seth-Olov
Astrazeneca AB
Chang Celia
White & Case LLP
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