Substituted C-furan-2-yl-methylamine and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S471000, C548S364100, C549S472000, C549S482000, C549S483000, C549S496000

Reexamination Certificate

active

06878740

ABSTRACT:
Substituted C-furan-2-yl-methylamine and C-thiophen-2-yl-methylamine compounds, processes for their preparation, medicaments and pharmaceutical compositions containing them, and their use in treatment methods and in the preparation of analgesics, in the preparation of a local anaesthetic, an antiarrhythmic, an antiemetic, a nootropic agent and/or a medicament for the treatment and/or prophylaxis of cardiovascular diseases, urinary incontinence, diarrhea, pruritus and/or inflammations, and/or a medicament for the treatment of depression and/or alcohol and/or drug and/or medicament abuse, and/or a medicament for increasing vigilance.

REFERENCES:
patent: 3816457 (1974-06-01), Grisar et al.
patent: 3890445 (1975-06-01), Grisar et al.
patent: WO-0168616 (2001-09-01), None
patent: WO-0244171 (2002-05-01), None
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K.G. Lewis et al, “Rearrangements in the Furan Series IV—The Reaction Between Furan-2-carbaldehyde and Aniline”Aust. J. Chem. (1990) 43:655-663.
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T. Obata et al. “Preparation of aminopyrimidines as insecticides and agrochemical fungicides”Chemical Abstractsvol. 115 (1991) p. 378.
N.A. Petasis et al. “One-step three-component reaction among organoboronic acids, amines and sallcylaidehydes”Tetrahedron Letters42 (2001) pp. 539-542.
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