Substituted biphenyl derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

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C564S164000

Reexamination Certificate

active

06946489

ABSTRACT:
The invention relates to compounds of the formula Iin which R1, R2, R3, R4and X have the meaning indicated in the text. The compounds act as inhibitors of factors Xa and VIIa and can therefore be employed for the control and prevention of thromboembolic conditions such as thrombosis, myocardial infarct, arteriosclerosis, inflammation, apoplexy, angina pectoris, restenosis after angioplasty and intermittent claudication.

REFERENCES:
patent: 5962695 (1999-10-01), Nagahara et al.
patent: 6545055 (2003-04-01), Zhu et al.
patent: 6638980 (2003-10-01), Su et al.
patent: 0540051 (1993-05-01), None
patent: 1078917 (2001-02-01), None
patent: WO 9941231 (1999-08-01), None
patent: WO 0071512 (2000-11-01), None

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