Substituted biphenyl derivatives

Details Substituted biphenyl derivatives Substituted biphenyl derivatives

1990-01-24

1991-04-23

Reamer, James H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

514562, 514535, 562455, 562432, 562426, 560 16, 560 43, A61K 31195

Patent

active

RE0335746

ABSTRACT:
Novel compounds which are 2,6-di-tertiary-butylphenols substituted in the 4 position by an acylaminophenyl group, which acylaminophenyl group is substituted by a moiety which includes a carboxyl group, are useful as inhibitors of leukotriene biosynthesis and as antiallergic agents.

REFERENCES:
patent: 4055653 (1977-10-01), Offermanns et al.
patent: 4067895 (1978-01-01), Hofer et al.
patent: 4094857 (1978-06-01), Wolfe
patent: 4153728 (1979-05-01), Wolff
patent: 4172151 (1979-10-01), Moore
Bailey et al., Ann. Rpts. Med. Chem., vol. 17, pp. 203-207 (1982).
Samuelsson, Science, vol. 220, pp. 568-575 (1983).

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