Substituted bicyclic 8-pyrrolidinoxanthines, methods for...

Details Substituted bicyclic 8-pyrrolidinoxanthines, methods for... Substituted bicyclic 8-pyrrolidinoxanthines, methods for...

2007-01-17

2010-11-23

Berch, Mark L (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S268000, C548S453000

Reexamination Certificate

active

07838528

ABSTRACT:
Compounds for the treatment of elevated blood glucose levels and the physiological and metabolic disorders arising therefrom are disclosed and comprise novel substituted bicyclic 8-pyrrolidinoxanthines and their derivatives of formula I:wherein the various R groups are hereinafter defined. The present invention also comprises pharmaceutical compositions comprising them as well as processes for the preparation of these compounds. Particular blood glucose disorders treatable thereby include type-2 diabetes, insulin resistance, hyperglycemia, arteriosclerotic diseases and the like.

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