Substituted biaryl amides C5a receptor modulators

Details Substituted biaryl amides C5a receptor modulators Substituted biaryl amides C5a receptor modulators

2007-11-06

2007-11-06

Solola, Taofiq (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S422000, C514S438000, C514S471000, C514S617000, C544S393000, C548S557000, C549S074000, C549S441000, C549S527000, C564S139000

Reexamination Certificate

active

11324729

ABSTRACT:
Substituted biaryl amides of Formula I are provided. Such compounds are ligands that may be used to modulate C5areceptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological C5areceptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies

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