Substituted .beta.-diketones

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514311, 514354, 514356, 514441, 514445, 514447, 514461, 514471, 514472, 514473, 514520, 514544, 514543, 514547, 514569, 514570, 514672, 514675, 514678, 514688, 546174, 546340, 546341, 546342, 549 60, 549 64, 549 66, 549 68, 549 69, 549 78, 549479, 549480, 549498, 558414, 560 80, 560 82, 560191, 560192, 560195, 560196, 560197, 560201, 562459, 562462, 562464, 562465, A61K 3138, A61K 312, C07C 49794, C07D33322

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052887502

ABSTRACT:
##STR1## wherein R.sub.1 and R.sub.2 are each independently hydrogen, alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, hydroxy, aryl or heteroaryl or amino, the alkyl, aryl, heteroaryl or amino group being optionally substituted; R.sub.3 is hydrogen, optionally substituted alkyl of 1 to 6 carbon atoms or optionally substituted aryl or heteroaryl and salts, ethers and esters thereof are useful as cytoprotective agents, especially as antitulcerogenic or gastroprotective agents.

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