Substituted .beta.-amino acid derivatives useful as platelet agg

Details Substituted .beta.-amino acid derivatives useful as platelet agg Substituted .beta.-amino acid derivatives useful as platelet agg

1992-10-06

1994-09-06

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

556465, 562440, C07C22934, C07C22942

Patent

active

053449576

ABSTRACT:
Novel substituted .beta. amino acid derivatives are provided which inhibit platelet aggregation. This invention also pertains to pharmaceutical compositions and methods of using such derivatives.

REFERENCES:
patent: 4517686 (1985-05-01), Ruoslahti et al.
patent: 4578079 (1986-03-01), Ruoslahti et al.
patent: 4589881 (1986-05-01), Pierschbacher et al.
patent: 4614517 (1986-09-01), Ruoslahti et al.
patent: 4661111 (1987-04-01), Ruoslahti et al.
patent: 4683291 (1987-07-01), Zimmerman et al.
patent: 4857508 (1989-08-01), Adams et al.
patent: 4879313 (1989-11-01), Tjoeng et al.
patent: 5039805 (1991-08-01), Alig et al.
patent: 5053393 (1991-10-01), Tjoeng et al.
patent: 5086069 (1992-02-01), Klein et al.
patent: 5220050 (1993-06-01), Bovy et al.
patent: 5272162 (1993-12-01), Tjoeng et al.
Koczewiak et al., Biochem. 23, 1767-1774 (1984).
Plow et al., Proc. Natl. Acad. Sci. 82, 8057-8061 (1985).
Ruggeri et al., Proc. Natl. Acad. Sci. 83, 5708-5712 (1986).
Haverstick et al., Blood 66 (4) 946-952 (1985).
Ruoslahti and Pierschbacher, Science 238, 491-497 (1987).
R. T. Boere et al., J. Organomet. Chem. 331, 161-167 (1987).
W. E. Parham, C. K. Bradsher, Acct. Chem. Res. 300 (1982).
M. Taddei and A. Ricci, Synthesis 633-635 (1986).
Ginsberg et al., J. Biol. Chem. 260 (7), 3931-3936 (1985).
C. F. Allen and J. W. Gates, Org. Synth. Coll. vol. 2 3 140 (1955).

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