Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1997-10-07
1999-07-13
Kumar, Shailendra
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514357, 514438, 514471, 514522, 514534, 514539, 514598, 514563, 546286, 546329, 549 60, 549 71, 549 72, 549474, 549496, 558417, 560 39, A61K 3117, C07C27506, C07C27528
Patent
active
059227672
ABSTRACT:
Disclosed herein are substituted benzylurea derivatives represented by the following general formula (1): ##STR1## wherein R.sup.1 and R.sup.2 are independently H, a halogen atom, or an alkyl or alkoxyl group, R.sup.3 is a phenyl or heterocyclic group which may be substituted, n is an integer of 1-6, and R.sup.4 is a phenyl group which may be substituted, or salts thereof, and medicines comprising such a derivative as an active ingredient. The derivatives or salts thereof strongly inhibit only ACAT in macrophages and are hence useful as prophylactic and therapeutic agents for arteriosclerosis.
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Hirota Hiroyuki
Ishii Fumio
Kanamaru Yoshihiko
Komoto Teruo
Naito Hiroyuki
Kumar Shailendra
SS Pharmaceutical Co., Ltd.
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