Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1992-12-07
1995-03-21
Ford, John M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
544123, C07D23934
Patent
active
053996917
ABSTRACT:
The present invention provides a substituted benzoylurea derivative having the formula (I), ##STR1## (wherein Q is a --R.sub.1 N(Z.sub.2)Z.sub.3 group or a --R.sub.2 N(Z.sub.4)COR.sub.1 N(Z.sub.2)Z.sub.3 group, R.sub.1 and R.sub.2 are respectively an alkanediyl group which may be substituted with a lower alkylthio group or a phenyl group, Z.sub.1, Z.sub.2, Z.sub.3 and Z.sub.4 are respectively a hydrogen atom or a lower alkyl group, R.sub.1 and Z.sub.2 may be bonded with each other to form a heterocyclic ring with an adjacent nitrogen atom, X is a halogen atom, a lower alkyl group or a CF.sub.3 group, and Y is a halogen atom) or its salt, effective as an antitumor agent; a method for producing the same; an antitumor composition containing the same; and an intermediate product for producing the same.
Kon Kenji
Okada Hiroshi
Ford John M.
Ishihara Sangyo Kaisha Ltd.
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