Substituted benzopyran analogs for the treatment of inflammation

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514312, 514250, 514290, 514285, 514292, 546156, 546153, 546101, 546 62, 546 81, 544350, 544345, A61K 3147, A61K 31495, A61K 3144, C07D21516, C07D22106

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active

060778504

ABSTRACT:
A class of benzopyrans, benzothiopyrans, dihydroquinolines, dihydronaphthalenes, and analogs thereof, is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I'wherein X, A.sup.1, A.sup.2, A.sup.3, A.sup.4, R, R", R.sup.1 and R.sup.2 are as described in the specification.

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