Substituted benzoic acid amides, their preparation and their...

Details Substituted benzoic acid amides, their preparation and their... Substituted benzoic acid amides, their preparation and their...

2005-01-04

2005-01-04

Kumar, Shailendra (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S538000, C548S539000, C548S518000, C546S276400, C514S381000, C514S423000, C514S340000

Reexamination Certificate

active

06838565

ABSTRACT:
Carboxylic acid amides of general formulahaving an antithrombotic activity and a factor Xa-inhibiting activity. Exemplary are:(a) N-[1-(3-amidino-phenyl)-2-(1H-tetrazol-5-yl)-ethyl]-4-(2,5-dihydro-pyrrol-1-yl-carbonyl)-3-methyl-benzamide,(b) N-[1-(3-amidino-phenyl)-2-(1H-tetrazol-5-yl)-ethyl]-3-methyl-4-(pyrrolidin-1-yl-carbonyl)-benzamide,(c) N-[1-(5-amidino-2-hydroxy-phenyl)-2-phenyl-ethyl]-3-methyl-4-(pyrrolidin-1-yl-carbonyl)-benzamide, and(d) N-[1-(5-amidino-2-hydroxy-phenyl)-2-(pyridin-3-yl)-ethyl]-3-methyl-4-(pyrrolidin-1-yl-carbonyl)-benzamide.

REFERENCES:
patent: 20020151534 (2002-10-01), Ries et al.
patent: WO 0156989 (2001-08-01), None
Copy International Search Report Reference #PCT/EP 03/07924, Nov. 2003.

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