Substituted benzo[e][1,4]oxazino[3,2-g]isoindole compounds

Details Substituted benzo[e][1,4]oxazino[3,2-g]isoindole compounds Substituted benzo[e][1,4]oxazino[3,2-g]isoindole compounds

2007-12-25

2007-12-25

Habte, Kahsay (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S099000

Reexamination Certificate

active

10531648

ABSTRACT:
A compound selected from those of formula (I):wherein:W1, with the carbon atoms to which it is bonded, represents phenyl or pyridyl,Z represents a group selected from hydrogen, halogen, linear or branched (C1-C6)alkyl, aryl, aryl-(C1-C6)alkyl, aryloxy, aryl-(C1-C6)alkoxy, hydroxy and linear or branched (C1-C6)alkoxy,R1is as defined in the description,R2represents hydrogen or —CH2CH2O—R8,R3and R4each represents hydrogen, linear or branched (C1-C6)alkyl, aryl or aryl-(C1-C6)alkyl,n represents an integer of from 1 to 6 inclusive,its isomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same which are useful in the treatment of cancer.

REFERENCES:
patent: 0841337 (1998-05-01), None
Motohashi,Pharmaceutical Society of Japan, 1983, 103, 364-371.
Morgan, et al.,Photochemistry and Photobiology, 2000, 71, 747-757.
International Search Report for International ApplicationNo. PCT/FR2003/03068, Feb. 23, 2004.
International Preliminary Examination Report for International ApplicationNo. PCT/FR2003/03068, Feb. 23, 2004.

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